These extra benefits help prevent cardiovascular (heart and blood vessel) disease in people who’ve had events like heart attacks and in people who are at risk. Make plaques (fatty deposits) less likely to break away and cause damage.Reduce the risk of blood clots by stopping platelets from sticking together.Reduce inflammation (swelling) and damage in your blood vessels.Improve the function of the lining of your blood vessels.Providers may also use the name HMG CoA reductase inhibitors when talking about statins. Statins decrease cholesterol by blocking the HMG CoA reductase enzyme that your liver uses to make cholesterol.

Providers choose these for most people because they work well and are considered first-line treatment for most people with elevated cholesterol. Statins are one of the better-known types of cholesterol-lowering drugs. Your healthcare provider will discuss these options with you and together, you can decide which type of high-cholesterol medication, if any, would be best for you.

Adenosine triphosphate-citrate lyase (ACL) inhibitors (Nexletol® and Nexlizet).

Omega-3 fatty acids and fatty acid esters (Epanova®, Lovaza® and others).

Selective cholesterol absorption inhibitors (Zetia® and Nexlizet®).

Nicotinic acid or niacin (Niacor® and Niaspan®).

Bile acid sequestrants or bile acid resins (Colestid®, Questran®, Locholest® and others).

Fibric acid derivatives or fibrates (Tricor®, Lopid®, Antara® and others).

PCSK9 inhibitors (Praluent®, Repatha® and Leqvio®).

Statins (Lipitor®, Crestor®, Zocor® and others).

Types of cholesterol-lowering drugs include: Your provider might discuss using different medications with you to lower your cholesterol, as well, depending on your personal risk factors. If diet and exercise aren’t enough to reach that goal, they might prescribe medicines. Your healthcare provider will discuss your personal risk factors and cholesterol goal.

What are antihyperlipidemic drugs used for?Īntihyperlipidemic drugs help you improve your cholesterol levels. The rest is extra, and that excess can lead to atherosclerosis and slow down blood flow in your blood vessels. A genetic issue that causes high cholesterol levels.Įveryone needs some cholesterol in their bodies, but your liver produces the cholesterol you need.Cholesterol and saturated fat in foods that come from animals (like meat and dairy products) and fried foods (including palm oil products).Many people have high cholesterol because of: All rights reserved.Antihyperlipidemic drugs are medicines that help you lower your cholesterol levels. However, the improvements in blood pressure and lipids demonstrated in the intervention group suggest that grapefruit should be further evaluated in the context of obesity and cardiovascular disease prevention.Ĭopyright © 2012 Elsevier Inc. This study suggests that consumption of grapefruit daily for 6 weeks does not significantly decrease body weight, lipids, or blood pressure as compared with the control condition. 001), respectively, compared with baseline values. Improvements were observed in circulating lipids of those consuming grapefruit, with total cholesterol and low-density lipoprotein significantly decreasing by -11.7 mg/dL (P =. 0002), and a significant reduction in systolic blood pressure (-3.21 ± 10.13 mm Hg, P =. 097), a significant reduction in waist circumference (-2.45 ± 0.60 cm, P =. Grapefruit consumption was associated with modest weight loss (-0.61 ± 2.23 kg, P =. No differences between group in weight, blood pressure, or lipids were demonstrated. Following a 3-week washout diet low in bioactive-rich fruits and vegetables, participants were randomized to either the control diet (n = 32) or daily grapefruit (n = 42) in the amount of one half of a fresh Rio-Red grapefruit with each meal (3× daily) for 6 weeks. The aim of this randomized controlled trial was to prospectively evaluate the role of grapefruit in reducing body weight and blood pressure and in promoting improvements in the lipid profile in overweight adults (N = 74). Sparse data exist to support this hypothesis, although there is some evidence of health promotion effects with regard to blood pressure control and modulation of circulating lipids. Folklore has suggested that consuming grapefruit may promote weight control.

Grapefruit and cholesterol meds